描述：Pentapharm總部位于瑞士Kaiseraugst 的DSM營養(yǎng)品公司，靠近巴塞爾，擁有日本、巴西等分支機(jī)構(gòu)在內(nèi)的200名員工，
蛋白酶抑制劑
合成，低分子量絲氨酸蛋白酶抑制劑。范圍包括競爭力，以及不可逆抑制劑。應(yīng)用：去除不需要的蛋白水解酶活性，增加色底物檢測的特異性或保護(hù)特定的蛋白質(zhì)水解降解。
099-11 | Pefabloc®FG | H-Gly-Pro-Arg-Pro-OH×AcOH |
| 099-01 | Inhibits fibrin polymerisation | |
| 126-05 | r-Hirudin | C287H440N80O110S6 |
| Inhibits thrombin | ||
| 380-03 | Pefabloc®PK | C24H26N4O3S×HCl |
| For the determination of plasma kallikrein | ||
| 381-01 | Pefabloc® TH | C27H31N5O4S×AcOH |
| For the determination of thrombin | ||
| 381-02 | Pefabloc®TH1158 | C27H32N6O4S×HCl |
| For the determination of thrombin | ||
| 382-03 | Pefabloc®uPA | C32H47N5O5S×HCl |
| For the determination of urokinase | ||
| 383-03 | Pefabloc®PL | C31H33N5O4S2×HCl |
| For the determination of plasmin | ||
| 384-01 | Pefabloc®Try | C14H12N2O2×HCl×H2O |
| For the determination of trypsin-like | ||
| 384-04 | Pefabloc®Try1405 | C26H29N5O5S×HCl |
| For the determination of trypsin | ||
| 385-02 | H-Glu-Gly-Arg-CMK | C14H25N6O5Cl×2TFA |
| For the determination of serine proteases | ||
| 385-03 | Pefabloc®Xa | C20H24N4O5S×HCl |
| For the determination of Factor Xa | ||
| 390-10 | Pefabloc®Tryp | C44H44N8O6S2×2HCl |
| For the determination of mast cell typtase | ||
| 391-03 | Pefabloc®tPA/Xa | C23H24N4O×2HCl |
| For the determination of tPA/Xa | ||
| 398-01 | Pefabloc®SP | C10H10N2O3×HCl |
| For the determination of trypsin-like serine proteases | ||
| 399-01 | Pefabloc®SC | C8H10FNO2S×HCl |
| For the determination of serine proteases | ||
| 800277 （1g） | Aprotinin | |
| 800348 （100g） | Inhibits serine proteases |
Chromogenic Substrates for Thrombin
081-01 | Pefachrome® TH 5244 | Tos-Gly-Pro-Arg-pNA ·AcOH |
| 081-03 | Pefachrome® TH | H-D-CHG-Ala-Arg-pNA · 2AcOH |
| 081-05 | Pefachrome® TH 5247 | H-D-CHG-But-Arg-pNA · 2AcOH |
| 081-08 | Pefachrome® TH 5250 | H-D-CHG-Pro-Arg-pNA · 2AcOH |
| 081-09 | Pefachrome® TH 5251 | H-D-CHA-Ala-Arg-pNA · 2AcOH |
| 081-10 | Pefachrome® TH 5252 | H-D-CHA-Gly-Arg-pNA · 2AcOH |
| 081-11 | Pefachrome® TH 5253 | H-D-CHA-Gly-Arg-pNA · 2AcOH |
| 081-15 | Pefachrome® TH 5256 | CH3OCO-Gly-Pro-Arg-pNA · AcOH |
| 081-17 | Pefachrome® TG | H-ß-Ala-Gly-Arg-pNA · 2AcOH |
| 081-66 | Pefachrome® TH 8198 | H-D-Phe-Pip-Arg-pNA · 2HCl S-2238 |
Chromogenic Substrates for Factor Xa
085-01 | Pefachrome® FXa5277 | CH3SO2-D-Leu-Gly-Arg-pNA · AcOH |
| 085-03 | Pefachrome® FXa5279 | CH3OCO-D-CHG-Gly-Arg-pNA · AcOH |
| 085-05 | Pefachrome® FXa5112 | C2H5OCO-D-Val-Gly-Arg-pNA · AcOH |
| 085-06 | Pefachrome® FXa | CH3OCO-D-CHA-Gly-Arg-pNA · AcOH |
| 085-26 | Pefachrome® FXa8592 | Cbo-Ile-Glu（γ-OR）-Gly-Arg-pNA · HCl （R=50% ME, 50% H） S-2222 |
| 085-27 | Pefachrome® FXa8595 | Cbo-D-Arg-Gly-Arg-pNA · 2HCl S-2765 |
Chromogenic Substrates for Factor VII
| 093-01 | Pefachrome® FVIIa | CH3SO2·-D-CHA-Abu-Arg-pNA · AcOH |
Chromogenic Substrates for Factor IXa
| 095-01 | Pefachrome® FIXa3960 | H-D-Leu-PHG-Arg-pNA · 2AcOH
|  |
| 095-02 | Pefachrome® FIXa | CH3SO2-D-CHG-Gly-Arg-pNA · AcOH |
Chromogenic Substrates for Factor XIIa
| 092-02 | Pefachrome® FXIIa | H-D-CHA-Gly-Arg-pNA · 2AcOH |
Chromogenic Substrates for Urokinase
| 082-01 | Pefachrome® uPA | Bz-ß-Ala-Gly-Arg-pNA · AcOH
| |
| 082-02 | Pefachrome® uPA5260 | Cbo-Glu（OtBu）-Gly-Arg-pNA ·. AcOH
| |
| 082-33 | Pefachrome® uPA8294 | pyro-Glu-Gly-Arg-pNA · 2HCl S-2444
| |
Chromogenic Substrates for Tissue Plasminogen Activator
| 091-01 | Pefachrome® tPA | CH3SO2-D-CHA-Gly-Arg-pNA · AcOH
| |
| 091-03 | Pefachrome® tPA5312 | CH3SO2-D-Phe-Gly-Arg-pNA · AcOH
| |
| 091-05 | Pefachrome® tPA5314 | CH3SO2-D-Abu-Gly-Arg-pNA · AcOH
|
Chromogenic Substrates for Plasmin
| 083-01 | Pefachrome® PL5261 | Tos-Gly-Pro-Lys-pNA · AcOH
| |
| 083-02 | Pefachrome® PL5262 | H-D-But-CHA-Lys-pNA · 2AcOH
| |
| 083-03 | Pefachrome® PL5263 | H-D-Nva-CHA-Lys-pNA · 2AcOH
| |
| 083-04 | Pefachrome® PL5264 | H-D-Nle-CHA-Lys-pNA · 2AcOH
| |
| 083-09 | Pefachrome® PL5268 | H-D-Ala-CHA-Lys-pNA · 2AcOH
| |
| 083-14 | Pefachrome® PL5272 | H-D-Nle-CHA-Lys-pNA · 2HCl |
| Chromogenic Substrates for Glandular Kallikrein |
| 088-01 | Pefachrome® GK | H-D-Val-CHA-Arg-pNA · 2AcOH |
Chromogenic Substrates for Plasma Kallikrein
| 080-01 | Pefachrome® PK 80714 | Bz Pro-Phe-Arg-pNA · AcOH
| |
| 080-03 | Pefachrome® PK | H-D-Abu-CHA-Arg-pNA · 2AcOH
| |
| 080-08 | Pefachrome® PK 8092Ca5295 | H-D-Pro-Phe-Arg-pNA · 2HCl S-2302 |
Chromogenic Substrates for Protein Ca
| 089-02 | Pefachrome® PCa | H-D-Lys（Cbo）-Pro-Arg-pNA · 2AcOH
| |
| 089-03 | Pefachrome® PCa5294 | H-D-CHA-Pro-Arg-pNA · 2AcOH
| |
| 089-04 | Pefachrome® PCa5295 | H-D-CHA-Pro-Arg-pNA · 2AcOH
| |
| 089-07 | Pefachrome® PCa5297 | Pad-Pro-Arg-pNA · AcOH
| |
| 089-08 | Pefachrome® PCa3297 | Pyr-CHG-Arg-pNA · AcOH |
Chromogenic Substrates for the Determination of C1-Esterase
| 087-01 | Pefachrome® C1E5292 | C2H5CO-Lys（Cbo）-Gly-Arg-pNA · AcOH
| |
| 087-02 | Pefachrome® C1E5293 | CH3OCO-Lys（Cbo）-Gly-Arg-pNA · AcOH
| |
| 087-03 | Pefachrome® C1E 5603 | CH3CO-Lys（Cbo）-Gly-Arg-pNA · AcOH |
Chromogenic Substrates for Trypsin
| 084-01 | Pefachrome® TRY5274 | Cbo-Val-Gly-Arg-pNA · AcOH
| |
| 084-03 | Pefachrome® TRY5276 | Cbo-Gly-D-Ala-Arg-pNA · AcOH
| |
| 084-04 | Pefachrome® TRY | Bz-Val-Gly-Arg-pNA · AcOH |
| Chromogenic Substrates for the Determination of Bacterial Endotoxins |
| 086-01 | Pefachrome® LAL5288 | CH3OCO-D-CHA-Gly-Arg-pNA · AcOH
| |
| 086-03 | Pefachrome® LAL5290 | CH3SO2·-D-Nle-Gly-Arg-pNA · AcOH
| |
| 086-06 | Pefachrome® LAL | CH3SO2-D-CHA-Gly-Arg-pNA · AcOH |
| 083-05 | Pefachrome® PL-Strept | plasminogen-streptokinase complex H-D-Nle-CHA-Arg-pNA · 2AcOH
| |
| 090-08 | Pefachrome® ELA | leucocyte elastase MeOSuc-Ala-Ala-Pro-Val-pNA
| |
| 090-12 | Pefachrome® PAP | papain 3-Phenylpropionyl-Pro-Phe-Arg-pNA · AcOH
| |
| 090-30 | Pefachrome® Col | collagenase （Clostridium histolyticum） Cbo-Gly-Pro-Leu-Gly-Pro-pNA
| |
| 090-35 | Pefachrome® Tryp | Tryptase, Plasmin Tos-Gly-Pro-Lys-pNA · AcOH |
| Fluorogenic Substrates for Thrombin |
| 081-19 | Pefafluor® TH | H-D-CHA-Ala-Arg-AMC · 2AcOH |
| 082-03 | Pefafluor® uPA | Bz-ß-Ala-Gly-Arg-AMC · AcOH |
| 085-12 | Pefafluor® FXa | CH3SO2-D-CHA-Gly-Arg-AMC · AcOH |
| 086-04 | Pefafluor® LAL5291 | CH3SO2·-D-CHA-Gly-Arg-AMC · AcOH |
| 089-05 | Pefafluor® PCa | Pyr-Pro-Arg-AMC · AcOH
| |
| 089-10 | Pefafluor® PCa3342 | Pyr-CHG-Arg-AMC · AcOH |
| 082-03 | Pefafluor® uPA | Bz-ß-Ala-Gly-Arg-AMC · AcOH |
| 091-06 | Pefafluor® tPA | CH3SO2-D-Phe-Gly-Arg-AMC · AcOH |
| 800049 | Pefafluor® MMP-2 Abz-Lys-Leu-Pro-Ala-Nva-Glu（pNA）-Ala-Arg-NH2 • 3TFA | Matrix metalloproteinase 2
| |
| 800050 | Pefafluor® MMP-7 Abz-Lys-Pro-Leu-Glu-Leu-Glu（pNA）-Ala Arg-NH2 • 3TFA | Matrix metalloproteinase 7 |
| 081-19 | Pefafluor® TH | H-D-CHA-Ala-Arg-AMC · 2AcOH |
| Activator | Source | Application | Remarks | |
| 113-01 / 113-04 | Protac® | • Determination of protein C and protein S • Protein C pathway assays | Serine protease Agkistrodon contortrix
| |
| 116-01 | Ecarin | • Prothrombin assay • Determination of hirudin | Metalloprotease, activates specifically prothrombin via meizothrombin, does not need PL and Ca2+ Echis carinatus
| |
| 119-02 | Convulxin | Activation of human plaets via binding and clustering of GPVI-receptors under physiological conditions | Crotalus durissus
| |
| 121-03 | RVV Factor V-Activator | Activation of FV in APC-R assay | Serine protease, not inhibited by AT
| |
| 121-06 | RVV-X | • Determination of FX • Screening assay for lupus anti-coagulants （diluted Russel viper venom test, dRVVT） | Metalloprotease, does also （weakly） activate protein C and factor IX Daboia （Vipera） russelli
| |
| 800191 | Pefakit® Reptilase® Time | Ready-to-use diagnostic reagent for measurement of • functionality of fibrin poly-merisation • afibrinogenemia or hypofibrinogen-emia • hyperfibrinolysis • thrombolytic therapy | CE-marked IVD Bothrops atrox | |
| 069-03 | Prionex® （sterile hydrolyzed gelatine） | Protein stabilization | |
| 116-10 | HEPES-buffer | Ecarin | |
| 148-03 | Gelatine 10% （solution） | Protein stabilization | |
| 801682 | Rabbit Brain Cephalin | Phospholipid source |
| Flyer |
| Pefakit® APC-R Factor V Leiden | ||
Pefakit® APC-R Factor V Leiden is a plasma based functional assay for the determination of resistance of Factor Va to inactivation by activated protein C （APC） caused by the factor V Leiden mutation （FV:Q506） | ||
| Pack: | 3 x 2 ml | APC /RVV-V （+APC） Reagent |
| 3 x 2 ml | RVV-V （-APC） Reagent | |
| 3 x 4 ml | PTA Reagent | |
| 3 x 2 ml | Dilution Plasma | |
| REF: | 502-01 | |
| Pefakit® APC-R Factor V Leiden Controls | ||
Control plasmas for confirmation of factor V Leiden mutation （FV:Q） in assays for determination of the functional phenotype for activated protein C resistance caused by the factor V Leiden mutation. | ||
| Pack: | 3 x 1 ml | FV-L Negative Control |
| 3 x 1 ml | FV-L Heterozygous Control | |
| REF: | 502-21 | |
| Pefakit® APC-R Factor V Leiden Homozygous Control | ||
Control plasma for confirmation of factor V Leiden mutation （FV:Q） in assays for determination of the functional phenotype for activated protein C resistance caused by the factor V Leiden mutation. | ||
| Pack: | 3 x 0.5 ml | FV-L Homozygous Control |
| REF: | 502-23 | |
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| Flyer |
Pefakit® in-TDT Determination of initial thrombin formation by intrinsic activation. Pack: 2 x 2 ml Reagent 2 x 2 ml Activator 2 x 2,5 ml Diluent 1 x 1 ml Calibrator 1 x 1 ml Control N 1 x 1 ml Control P REF: 800236 |
You can order your free manual and adaption protocol by clicking on the contact option on top of the screen.
- Manual for the Analysis Software Tool BCS®
- BCS Adaption protocol for Pefakit® in-TDT® Art. 800236
- Manual for the Analysis Software Tool ACL 9000
- ACL-9000 Adaption protocol for Pefakit® in-TDT® Art. 800236
| Flyer |
Pefakit® PiCT® - Prothrombinase induced Clotting Time | ||
Pefakit® PiCT® is a plasma based functional assay for the determination of factor Xa and factor IIa inhibitors. | ||
| Pack: | 3 x 2 ml | PiCT® Activator |
| 3 x 2 ml | PiCT® Start Reagent | |
| REF: | 505-01 | |
| Applications for various haemostasis systems on request Applications for direct factor Xa inhibitors on request | ||
| Pefakit® PiCT® Calibrators UFH | ||
| Pack: | 3 x 1 ml | UFH Calibrator 1 |
| 3 x 1 ml | UFH Calibrator 2 | |
| REF: | 505-121 | |
| Pefakit® PiCT® Controls UFH | ||
| Pack: | 3 x 1 ml | UFH Control 1 |
| 3 x 1 ml | UFH Control 2 | |
| REF: | 505-22 | |
| Pefakit® PiCT® Calibrators LMWH | ||
| Pack: | 3 x 1 ml | LMWH Calibrator 1 |
| 3 x 1 ml | LMWH Calibrator 2 | |
| REF: | 505-11 | |
| Pefakit® PiCT® Controls LMWH | ||
| Pack: | 3 x 1 ml | LMWH Control 1 |
| 3 x 1 ml | LMWH Control 2 | |
| REF: | 505-21 | |
| Pefakit® PiCT® Calibrators Hirudin | ||
| Pack: | 3 x 1 ml | Hirudin Calibrator 1 |
| 3 x 1 ml | Hirudin Calibrator 2 | |
| REF: | 505-13 | |
| Pefakit® PiCT® Controls Hirudin | ||
| Pack: | 3 x 1 ml | Hirudin Controls 1 |
| 3 x 1 ml | Hirudin Controls 2 | |
| REF: | 505-23 | |
